Modules 17b - Myocardial Blood Flow with 82Rb PET Imaging Case Reviews-Myocardial Blood Flow with 82Rb PET Imaging Case Reviews (Presentation)

Video Transcription

Video Summary

In this video, Mouaz Mellah, the Director of Cardiovascular PET at Houston Methodist DeBakey Heart and Vascular Institute, discusses several cases related to cardiovascular blood flow with rubidium perfusion imaging. Mellah highlights the importance of quality control for blood flow data, the findings from rubidium PET images, and the effective use of gated information in imaging and diagnosis.<br /><br />In the first case study, an 81-year-old woman with a history of hypertension and dyslipidemia undergoes evaluation for chest pain. The rubidium perfusion images reveal normal perfusion without any defects. Gated images show normal ventricle augmentation and no regional wall motion abnormalities. The patient's resting ejection fraction is 67% and increases to 73% with vasodilator stress. Myocardial blood flow imaging shows elevated resting flow and a threefold increase in stress flow, resulting in a global myocardial flow reserve of 3. Coronary angiography confirms no evidence of obstructive disease, indicating low likelihood of obstructive coronary disease despite extensive coronary artery calcification.<br /><br />Additional cases include a 58-year-old woman with aortic stenosis, a 60-year-old man with hypertension and dyslipidemia, a 74-year-old man with end-stage renal disease, and a 65-year-old man with known coronary artery disease. These cases illustrate the importance of evaluating input function quality, identifying misregistration artifacts, and addressing technical issues in obtaining accurate myocardial blood flow measurements.<br /><br />In summary, the video emphasizes the use of rubidium perfusion imaging to assess myocardial blood flow, the integration of various findings in diagnosis, and the significance of quality control in obtaining reliable results.

Keywords

cardiovascular blood flow

rubidium perfusion imaging

quality control

gated information

chest pain evaluation

myocardial blood flow imaging

obstructive coronary disease