Module 15. Cardiac Sarcoid PET Imaging Clinical Data-Cardiac Sarcoid PET Imaging Clinical Data (Slides)

Cardiac Sarcoid PET Imaging Clinical Data (Slides)

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This document provides clinical data and information regarding the use of FDG-PET imaging for cardiac sarcoidosis. It highlights the importance of patient preparation for FDG-PET imaging and describes various methodologies for interpreting the results. The document also discusses the use of FDG-PET for the diagnosis, prognosis, and response to treatment of cardiac sarcoidosis.<br /><br />It references expert consensus documents from the Society of Nuclear Medicine and Molecular Imaging, the American Society of Nuclear Cardiology, and the European Association of Nuclear Medicine, among others. These documents provide recommendations and guidelines for the role of PET/CT in detecting and monitoring therapy for cardiac sarcoidosis.<br /><br />The document emphasizes the prevalence and significance of cardiac involvement in sarcoidosis, with up to 70% of deaths in sarcoidosis patients being cardiac-related. It also highlights the non-specific or absent symptoms of cardiac sarcoidosis, making diagnosis challenging.<br /><br />Patient preparation for FDG-PET imaging includes prolonged fasting, a high-fat/low-carbohydrate diet, and the avoidance of certain medications. A food diary is provided as a tool for patients to track their diet leading up to the exam.<br /><br />Interpretation of FDG-PET images involves visual analysis of normalized, angle-corrected images to identify patterns of uptake. Quantitative analysis using standard uptake values (SUV) and heart-to-blood pool ratios can also aid in evaluating disease progression and treatment response.<br /><br />The document emphasizes the importance of evaluating for extra-cardiac sarcoidosis through chest radiographs, skin exams, ophthalmological evaluations, and laboratory tests. It also provides case examples and illustrations to illustrate the role of FDG-PET in the diagnosis and management of cardiac sarcoidosis.<br /><br />In conclusion, FDG-PET imaging plays a crucial role in the diagnosis and management of cardiac sarcoidosis. It requires detailed patient preparation and interpretation techniques, and can provide valuable information for determining the need for immunosuppressive therapy.

Keywords

FDG-PET imaging

cardiac sarcoidosis

patient preparation

diagnosis

prognosis

response to treatment

expert consensus documents

PET/CT

extra-cardiac sarcoidosis

immunosuppressive therapy