Module 11. Cardiac PET Myocardial Perfusion Imaging Including Myocardial Blood Flow Assessment in Clinical Studies-Cardiac PET Myocardial Perfusion Imaging Including Myocardial Blood Flow (Slides)

Cardiac PET Myocardial Perfusion Imaging Including Myocardial Blood Flow (Slides)

Pdf Summary

Part 5 of the document discusses cardiac PET myocardial perfusion imaging (MPI) and the assessment of myocardial blood flow (MBF) in clinical studies. The module outlines the clinical applications of PET MPI, the differences between PET and SPECT MPI, and methods to reduce radiation exposure with PET/CT MPI. It emphasizes the importance of MBF assessment with PET and highlights the benefits of PET in terms of spatial and contrast resolution, count density, and attenuation and scatter correction compared to SPECT. The module also discusses the role of PET in diagnosing and providing prognostic information for coronary artery disease (CAD), including its ability to improve risk stratification and prognostic models. It further explores the use of MBF quantification to help diagnose different types of CAD, evaluate microvascular dysfunction, and assess the significance of known obstructive CAD or chronic total occlusion. The document also covers the use of PET in measuring left ventricular ejection fraction (LVEF), identifying stress-induced wall motion abnormalities, and assessing the response to vasodilators and caffeine. The module concludes by discussing the incremental prognostic value of MBF and the benefits of revascularization in patients with reduced MBF and worsening ischemia. It emphasizes the advantages of PET in terms of resolution, image quality, radiation dose, diagnostic accuracy, and blood flow quantification, making it a valuable tool in clinical studies for assessing cardiac perfusion and MBF.

Keywords

cardiac PET myocardial perfusion imaging

assessment of myocardial blood flow

clinical applications of PET MPI

differences between PET and SPECT MPI

MBF quantification for diagnosing CAD

evaluation of microvascular dysfunction

measuring LVEF with PET

stress-induced wall motion abnormalities

response to vasodilators and caffeine

advantages of PET in cardiac perfusion assessment